Here is the structured PICO analysis for the thirty-fifth article you uploaded:
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Full Title (verbatim and exact):
“Developing evidence-based guidance for assessment of suspected infections in care home residents”
Hughes C, Ellard DR, Campbell A, et al.
BMC Geriatrics (2020); 20:59
DOI: https://doi.org/10.1186/s12877-020-1467-6
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Type of Article:
Multi-method development and consensus study (literature review, qualitative interviews, consensus meeting)
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PICO Analysis:
Population:
- Older residents of UK care homes (residential and nursing), including those with and without dementia
- Care home staff, general practitioners (GPs), geriatricians, microbiologists, and family members of residents participated in the development process
- Stakeholders drawn from care homes in Northern Ireland and the West Midlands (England)
Intervention:
- Revised decision-making algorithm for the recognition and management of:
- Urinary Tract Infections (UTIs)
- Respiratory Tract Infections (RTIs)
- Skin and Soft Tissue Infections (SSTIs)
- The updated tool includes:
- Initial assessment – non-specific and specific signs of infection
- Observation phase – with temperature thresholds and symptom review
- Action phase – based on symptom criteria for escalation (e.g. call GP, monitor)
- Also includes supportive care (e.g. fluids, paracetamol, observe), and was designed for use by both nursing and non-nursing staff
Comparator:
- The updated algorithm is a refinement of an earlier Canadian tool (Loeb et al., 2005)
- The new algorithm was compared against:
- Existing care home practice
- Stakeholder perceptions
- Latest evidence from literature (6 studies included)
- No randomised trial or direct comparator intervention was conducted
Outcome:
1. Person-centred outcomes:
- Not directly assessed in this development study
- Anticipated outcomes include:
- Improved recognition of infection
- Reduced unnecessary antibiotic use
- Better alignment of decisions with resident condition and preferences
- Empowerment of care home staff to confidently escalate concerns
2. Process outcomes:
- Strong focus on aligning the algorithm with:
- Current clinical evidence
- Usual practice realities
- Stakeholder (staff, GP, family) perceptions
- Staff found that it reflected usual practice, though noted:
- Variability in temperature-taking access (non-nurses often prohibited)
- Difficulties applying symptom criteria in residents with dementia
- Concerns about strict wait times for observation before GP contact
3. Health system outcomes:
- Intended system impacts include:
- Reduced inappropriate antibiotic prescribing
- Fewer unnecessary GP calls or ED transfers
- Standardised, evidence-based triage support for infections in aged care
- Participants agreed it could improve antimicrobial stewardship when paired with training
Summary Conclusion:
This study developed and refined an evidence-based, UK-contextualised algorithm for care home staff to manage suspected infections (UTI, RTI, SSTI). The algorithm includes a three-step structure (assessment, observation, action) and was built using literature review, stakeholder consensus, and field interviews. It addresses concerns such as dementia-related diagnostic complexity, nurse vs non-nurse skill sets, and real-world application. The tool represents a promising support for antimicrobial stewardship and safer infection recognition in care homes, pending full implementation and outcome evaluation.
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