Here is the standardised PICO analysis for the fourth uploaded article:
Full Title
Effectiveness of advance care planning programmes in improving end-of-life outcomes for individuals with dementia and their caregivers in nursing homes: protocol for a systematic review and meta-analysis
Authors: Yu-Tai Lo, Yi-Jhen Chen, Jheng-Yan Wu, Chih-Cheng Lai
Journal: BMJ Open, 2024; 14:e088646
DOI: 10.1136/bmjopen-2024-088646
Type of Study
Protocol for a systematic review and meta-analysis
PICO Summary
Population (P)
- Individuals with dementia residing in nursing homes, and their caregivers
- Includes adults aged 65+ with advanced cognitive decline, likely nearing end of life
- Reflects global populations, but special attention to studies in the US, UK, and Europe
- Also includes family caregivers as secondary population
Intervention (I)
- Advance Care Planning (ACP) programmes
- May include:
- Structured EoL conversations
- Documentation of advance directives
- Family-inclusive decision-making
- Multicomponent ACP interventions (education, discussion, and documentation)
- May include:
Comparison (C)
- Usual care (no formal ACP programme)
- May include informal or inconsistent EoL care planning
Outcomes (O)
Person-centred outcomes:
- Quality of life (patient-focused)
- Caregiver satisfaction
Process outcomes:
3. Advance directives completion rate (proportion with documented EoL preferences)
4. Uptake of ACP discussion (frequency of ACP conversations)
Health system outcome:
5. Comfort in the last week of life
- Captures alignment of care with patient wishes and symptom management
Findings Summary (Protocol Stage)
- No results yet: this is a protocol, not a completed review
- Will include RCTs and observational studies
- Designed using PRISMA-P, Cochrane methods, and GRADE certainty framework
- Aims to synthesise evidence across multiple EoL domains (clinical, emotional, communicative)
- Seeks to inform best practice guidelines and future ACP implementation strategies in long-term care settings
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