Here is the standardised PICO analysis for the article titled:
Full Title
A Framework for Cross-Cultural Development and Implementation of Complex Interventions to Improve Palliative Care in Nursing Homes: The PACE Steps to Success Programme
Authors: Jo Hockley, Katherine Froggatt, Lieve Van den Block, et al.
Journal: BMC Health Services Research, 2019; 19:745
DOI: 10.1186/s12913-019-4587-y
Type of Study
Implementation research and framework development paper using mixed qualitative data and process observations from a cluster randomised controlled trial (RCT) conducted across seven European countries.
PICO Summary
Population (P)
- Nursing home residents in 78 nursing homes across seven European countries
- Indirect participants: over 3,600 nurses and care assistants, nursing home managers, trainers, and PACE coordinators
Intervention (I)
PACE Steps to Success Programme
- A structured six-step palliative care intervention:
- Discussions about current and future care
- Assessment and review
- Monthly multidisciplinary palliative care review meetings
- Symptom management (especially pain and depression)
- Care in the last days of life
- Care after death
- Implemented using a train-the-trainers cascade model:
- International trainers → Country trainers → PACE coordinators → Frontline nursing home staff
- Cross-cultural adaptation of training materials, documentation, symptom tools, and delivery methods to suit local legal, ethical, and cultural norms
Comparison (C)
- Not explicitly a comparison study, though the paper discusses cross-national differences in implementation and adaptation outcomes
- Evaluation occurred across intervention vs control arms in the broader RCT (reported elsewhere)
Outcomes (O)
Implementation outcomes:
- Development of a three-phase framework:
- Adaptation and preparation of resources
- Training and delivery
- Ongoing facilitation and support
- Cross-cultural adaptation accounted for:
- Language
- Disclosure practices
- Legal barriers (e.g., around advance directives, opioid prescribing)
- Hierarchies in clinical roles (e.g., nurse vs physician status)
Process outcomes:
- Training conducted for 16 national trainers, 73 PACE coordinators, and hundreds of nursing staff
- Tools translated and tested in two non-trial homes in each country for feasibility and acceptability
- Facilitation needs were high, especially in countries where palliative care was less integrated or where cultural norms discouraged direct end-of-life conversations
Challenges identified:
- Staff turnover, limited internet access, and variable use of educational materials
- PACE coordinators often lacked formal authority to lead change
- Online peer support (e.g., a Facebook group in the UK) helped address staff isolation
- Not all nursing home managers gave consistent support; leadership buy-in was key
Conclusion
The PACE programme is a feasible and adaptable framework for improving palliative care in nursing homes through structured implementation, multilevel training, and cross-cultural adjustment. Its success depends on both internal champions and external facilitation, especially in settings with low baseline familiarity with palliative care.
This paper provides a valuable roadmap for implementing complex health interventions across diverse linguistic, clinical, and regulatory environments—balancing fidelity with local flexibility .
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